Browsing by Author "Heredia Zelaya, A"

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    Factors influencing outcomes of older children with medulloblastoma over 15 years in Peru, a resource-limited setting
    (John Wiley and Sons Inc, 2022) Diaz-Coronado, RY; Reinecke, JB; Stanek, JR; Finlay, JL; Hernández-Broncano, E; Chávez-Paredes, S; Miranda-Tunque, Y; Heredia Zelaya, A; Casavilca-Zambrano, S; García-Corrochano Medina, P; Ojeda Medina, L; Orrego Puelles, E; Torres Malca, E; Sernaque-Quintana, R; Quispe-Valverde, W; García León, JL; Osorio, DS
    Background: Medulloblastoma is the most common malignant brain tumor in children. While survival has improved in high-income countries (HIC), the outcomes for patients in low-to-middle-income countries (LMIC) are unclear. Therefore, we sought to determine the survival of children with medulloblastoma at the Instituto Nacional de Enfermedades Neoplasicas (INEN) between 1997 and 2013 in Peru. Methods: Between 1997 and 2013, data from 103 children older than 3 years with medulloblastoma were analyzed. Fourteen patients were excluded. The patients were split into two distinct cohorts, 1997–2008 and 2009–2013, corresponding with chemotherapy regimen changes. Event-free (EFS) and overall survival (OS) were calculated using the Kaplan–Meier method, whereas prognostic factors were determined by univariate analysis (log-rank test). Results: Eighty-nine patients were included