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Browsing by Author "Dreser Mansilla, A"

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    Point prevalence survey of antibiotic use in hospitals in Latin American countries
    (Oxford University Press, 2022) Levy Hara, G; Rojas-Cortes, R; Molina León, HF; Dreser Mansilla, A; Alfonso Orta, I; Rizo-Amezquita, JN; Santos Herrera, RG; Mendoza De Ayala, S; Arce Villalobos, M; Mantilla Ponte, H; Davila E; Aguilar, G; Porrás, A; Ramón-Pardo, P; Castro, JL; Guzmán, D; Rioseco, ML; Labarca, J; Madriz, JPD; Cubero, JM; Calderón AR; Alfaro, M; Soto, LA; Aayon, A; Oreamuno, TJ; Jimenez, Z; Sequeira, A; Hernández, JM; Lavaut, JLC; Meriño, DC; Ruisanchez, EF; Sánchez, DP; Garcell, HG; Socias, JJP; Diáz, EP; Lunar, NAC; Lancis, IF; Ramírez, JAÁ; Leyte, ML; Rosabal, AM; Estrada, EA; Cano, M; Mendez, L; Eiriz, AC; Menendez, LP; Fernández, GF; Ayala, RR; Monroy, S; Menjívar, R; Martínez, CEA; Cabrera, D; Delgado, SMM; Guzmán, GAM; Mejiá, R; Rodríguez, C; Alvarenga, S; Alvarado, M; De Zelaya, RDCA; Arevalo, G; Parada, G; Cuellar, L; Ruiz, AH; Pinedo, YA; Vergaray, ES; Gil, LEV; Ibazeta, BGI; Ricra, EDG; Segura, RE; Apac, CG; Inga, JC; Diáz, RH; Vigo, MV; Cuba, CM; Vilcapoma, P; Angles-Yanqui, E; Terrones, DRM; Robles, RT; Resurrección, C; Gonzalez, AC; Antezana, M; Zegarra, ST; Villegas-Chiroque, M; Diáz-Sipión, R; Benítez-Peche, J; Rosas, JLA; Ruiz, JLG; Fernández, AMH; Vargas, JAF; Araujo, J; Garciá, FJA; Rivera, ZC; Colín, VM; Ríos, KB; Blanquel, JIH; De La Garza, EA; Gutierrez, HH; León, K; Lara, HEP; Arias, CB; Garay, EA; Sanabria, GE; Menchaca, LM; Vire, NL; Acuña, D; Caballero, EG
    Background: Point prevalence surveys (PPSs) on antibiotic use are useful for understanding different aspects related to prescription patterns in hospitals. Methods: An adaptation of the WHO methodology for a PPS on antibiotic use was applied. Hospital wards were divided into medical (MED), surgical (SUR), ICUs, gynaecology and obstetrics (GO), high-risk (HR) and mixed wards (MIX). A web application (RedCapVC ) through a mobile device was used for data collection. Results: Between December 2018 and August 2019, 5444 patients in 33 hospitals in five countries were included (10 hospitals in Cuba, 7 in Paraguay, 6 in El Salvador, 5 in Mexico and 5 in Peru). Of these patients, 54.6%received at least one antibiotic, with variations between and within hospitals and countries. Antibiotics were more frequently used in ICUs (67.2%), SUR (64.5%) and MED wards (54.2%), with 51.2% of antibiotics prescribed for community-acquired infections (CAIs), 22.9% for healthcare-associated infections (HAIs), 11.1% for surgical prophylaxis and 6.1% for unknown reasons. Adherence to guidelines was observed in 68.6% of cases (72.8% for CAIs, 72.4% for HAIs and 44.3% for prophylaxis). Third-generation cephalosporins were the class of antibiotics most frequently used (26.8%), followed by carbapenems (10.3%) and fluoroquinolones (8%). Targeted treatments were achieved in 17.3%of cases. Conclusions: Antibiotic use was generally higher than that published in other studies. There is an urgent need to promote and strengthen the antimicrobial stewardship programmes in Latin America.

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